Best IVF Clinic in Thane

Pre-Implantation Genetic Testing in Thane

What is Pre-implantation genetic testing (PGT)?

Pre-implantation genetic testing is an early form of pre-natal genetic diagnosis, which is usually carried out on embryos prior to embryo transfer to determine genetic abnormalities. Those embryos which are genetically normal will be used for embryo transfer procedure.

What is the purpose of Pre-implantation genetic testing?

PGT helps to reduce the risk of miscarriage, a complication related to pregnancy failure, prevent undesired genetic traits and thereby improving the chances of a viable pregnancy.

PGT includes:
  • PGT-A (for aneuploidies): Used to check whether the embryos has correct number of chromosomes.

Indications:

  • Advanced maternal age
  • Multiple previous failed IVF attempts
  • Repeated miscarriages
  • Previous history of pregnancy with chromosomal abnormality
  • Previous history of child born with chromosomal abnormality
  • PGT-M (for monogenic/single gene defect): used to check for a specific gene defect or for inherited mutations which is carried by one or both the biological parent.

Indications:

Carrier of single gene disorders like:
    • Beta-thalassemia
    • Cancer predisposition genes (BRCA1/2, Lynch Syndrome, and others)
    • Cystic fibrosis
    • Duchenne muscular dystrophy
    • Fragile X syndrome
    • Huntington disease
    • Retinoblastoma
    • Sickle cell anemia
    • Tay-Sach disease
  • One or both partners or family history of heritable genetic disorders
  • One or both partners is a carrier of chromosomal abnormality
  • Couples who have child/children affected by a single gene disorder.
  • PGT-SR (for chromosomal structural rearrangements): used to identify balanced translocation, or deletion/duplication. Newer technologies allows to distinguish normal non-carrier embryos from balanced carriers.

How is the Pre-implantation testing procedure carried out?

Pre-implantation genetic testing requires the couple or individual to undergo egg collection followed by Intra-cytoplasmic sperm injection procedure (ICSI).   

    
Stages of PGT:

Fertility Treatments

Let's Meet Up

contact

Name(Required)
City(Required)

Our Latest Articles

After How Many Weeks IVF Pregnancy Is Safe?

After How Many Weeks IVF Pregnancy Is Safe?

Overview When you’ve walked the emotionally intense road of fertility treatment, the one question that keeps surfacing is: after how many weeks IVF pregnancy is safe? https://www.youtube.com/watch?v=pcdBLjm0Ypk For many hopeful parents, those first few weeks after an embryo transfer feel both exciting and terrifying. And understandably so. IVF isn’t just

Read More »
Night Sweats

Waking Up Drenched? Here’s What You Need to Know About Night Sweats

Overview Imagine waking up in the middle of the night, drenched in sweat, heart pounding, sheets soaked. If this sounds familiar, you’re not alone. Night sweats are more than just overheating – they can be a frustrating symptom of deeper issues, particularly for women experiencing hormonal changes. So, what’s really going

Read More »

Our Latest Articles

Scroll to Top